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Down's Syndrome Links

Down syndrome affects people of all ages, races and economic levels. It is the most frequently occurring chromosomal abnormality, occurring once in approximately every 800 to 1,000 live births. Over 350,000 people in the United States alone have Down syndrome.

Down syndrome is usually caused by an error in cell division called non-disjunction. However, two other types  of chromosomal abnormalities, mosaicism and translocation, are also implicated in Down syndrome – although to a much lesser extent. Regardless of the type of Down syndrome which a person may have, all people with Down syndrome have an extra, critical portion of the number 21 chromosome present in all, or some, of their cells. This additional genetic material alters the course of development and causes the characteristics associated with the syndrome.

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